{"id":90106,"date":"2026-07-13T09:00:00","date_gmt":"2026-07-13T06:00:00","guid":{"rendered":"https:\/\/desu.tr\/?p=90106"},"modified":"2026-07-13T09:00:00","modified_gmt":"2026-07-13T06:00:00","slug":"durasheet-collagen-dura-membrane-cranial-spinal","status":"publish","type":"post","link":"https:\/\/desu.tr\/tr\/durasheet-collagen-dura-membrane-cranial-spinal","title":{"rendered":"DURASHEET Collagen Dura Membrane for Cranial and Spinal Use"},"content":{"rendered":"<p><strong>DURASHEET collagen dura membrane<\/strong> is Desu Medical&#8217;s single-use biological dural substitute, produced from more than 99.9% pure Type I bovine collagen. It is engineered for cranial and spinal neurosurgical repair where the surgeon needs a compliant membrane that seals immediately and then hands the reconstruction over to the patient&#8217;s own tissue.<\/p>\n<h2>The Clinical Problem DURASHEET Addresses<\/h2>\n<p>In complex neurosurgical procedures the integrity of the dura mater is frequently compromised. Trauma, tumour resection, congenital malformation and spinal decompression all create defects that must be closed reliably. Failure to restore dural continuity invites cerebrospinal fluid leakage, infection and reoperation. Therefore the replacement material has to deliver mechanical closure and biological compatibility in the same product.<\/p>\n<h2>Material and Composition<\/h2>\n<p>DURASHEET is a collagen-based implant made from medical-grade Type I bovine collagen purified to more than 99.9%. It serves as a biological substitute for the dura mater, providing a natural and highly biocompatible scaffold that supports tissue integration, sealing and healing.<\/p>\n<p>Because collagen is the fundamental structural protein already present in native dura, the interface between graft and host is biologically familiar. Consequently, fibroblast migration and matrix deposition proceed without the encapsulation response associated with permanent foreign materials.<\/p>\n<h3>Sterilisation and Presentation<\/h3>\n<p>The membrane is single-use and terminally sterilised by gamma irradiation. It is supplied ready for the surgical field with no rehydration or preparation step. Each unit is individually packaged with lot traceability and expiry marking.<\/p>\n<h2>Handling Profile<\/h2>\n<p>The <strong>DURASHEET collagen dura membrane<\/strong> is designed for surfaces that are not flat. Cranial convexity, posterior fossa contours and spinal dural tubes all demand a membrane that conforms without buckling. DURASHEET can be trimmed with surgical scissors, positioned with forceps, and either sutured into the dural edge or laid as an onlay.<\/p>\n<p>Furthermore, the membrane retains its properties in contact with blood and irrigation, so it does not shrink away from the repair margin during closure.<\/p>\n<h2>Where DURASHEET Is Used<\/h2>\n<ul>\n<li><strong>Tumour resection.<\/strong> Reinforcing dural closure after excision, including skull base approaches.<\/li>\n<li><strong>Neurotrauma.<\/strong> Reconstructing dural defects caused by penetrating or blunt injury.<\/li>\n<li><strong>Spinal decompression.<\/strong> Repairing incidental or planned durotomy.<\/li>\n<li><strong>Decompressive craniectomy.<\/strong> Expansive duraplasty where the native dura cannot be closed primarily.<\/li>\n<\/ul>\n<p>In each of these settings the objective is the same: an immediate watertight barrier followed by biological remodelling.<\/p>\n<h2>Resorption and Long-Term Behaviour<\/h2>\n<p>DURASHEET is resorbable. Endogenous enzymatic activity gradually breaks down the collagen scaffold while host fibroblasts deposit new connective tissue in its place. As a result, no secondary procedure is required to remove the graft, and no permanent implant remains at the repair site to complicate future imaging or reoperation.<\/p>\n<h2>Quality System and Certification<\/h2>\n<p>Desu manufactures the dural graft range under an <a href=\"https:\/\/www.iso.org\/\" target=\"_blank\" rel=\"noopener\">ISO 13485<\/a> certified quality management system, with CE certification for the product line. Biocompatibility has been evaluated to the ISO 10993 series, covering cytotoxicity, sensitisation, systemic toxicity and implantation response. In addition, mechanical durability, absorption behaviour and tissue integration have been assessed as part of the technical documentation.<\/p>\n<p>Hospitals and distributors requiring the full technical file, declaration of conformity or lot documentation can request it from <a href=\"mailto:sales@desu.tr\">sales@desu.tr<\/a>.<\/p>\n<h2>DURASHEET or DECOLL?<\/h2>\n<p>Both membranes share the same >99.9% pure Type I bovine collagen specification. <a href=\"https:\/\/desu.tr\/tr\/urun\/decoll-collagen-dura-membrane\/\">DECOLL<\/a> is supplied in four defined square formats with dual-surface usability and an impermeable pore structure. DURASHEET offers a compliant profile suited to contoured anatomy. Many departments stock both and select per case. The complete range is documented at <a href=\"https:\/\/desu.tr\/tr\/urun\/dura-grafts\/\">desu.tr\/<\/a>.<\/p>\n<h2>Frequently Asked Questions<\/h2>\n<h3>Is DURASHEET synthetic?<\/h3>\n<p>No. It is a natural collagen implant made from purified Type I bovine collagen, not a manufactured polymer.<\/p>\n<h3>Can DURASHEET be sutured?<\/h3>\n<p>Yes. It holds sutures and may equally be applied as a sutureless onlay depending on defect geometry.<\/p>\n<h3>What sizes are available?<\/h3>\n<p>Size and packaging options are listed in the current catalogue. Our team can confirm availability for your market at <a href=\"mailto:sales@desu.tr\">sales@desu.tr<\/a>.<\/p>\n<h2>Conforming to Contoured Anatomy<\/h2>\n<p>Flat test surfaces are not the operating field. Cranial convexity curves in two planes, the posterior fossa is irregular, and the spinal dural tube is cylindrical. A membrane that behaves well on a bench and buckles on a curve creates dead space, and dead space at a dural repair is where fluid collects.<\/p>\n<p>DURASHEET is designed to sit against these surfaces without tenting or folding. Furthermore, the material retains its properties once wet, so it does not stiffen or shrink away from the margin during the remainder of the closure.<\/p>\n<h2>Single Use, and Why That Matters<\/h2>\n<p>Both Desu membranes are single-use devices. Each unit is terminally gamma sterilised and individually packaged with lot traceability and expiry marking. Offcuts from an opened sheet are not intended for another patient, and reprocessing is not supported. This is standard practice for implantable collagen and it protects both sterility assurance and the traceability chain that vigilance reporting depends on.<\/p>\n<h2>Integrating DURASHEET into a Departmental Protocol<\/h2>\n<ul>\n<li><strong>Define the default.<\/strong> Choose a standard membrane for routine closure so the material is not a per-case decision.<\/li>\n<li><strong>Define the exceptions.<\/strong> Identify the case types where a different format or size is preferred.<\/li>\n<li><strong>Set par levels.<\/strong> Cover emergency volume as well as the scheduled list.<\/li>\n<li><strong>Document the rationale.<\/strong> Tender and governance committees will ask, and the technical file answers most of it.<\/li>\n<\/ul>\n<p>Our clinical team supports departments through this process, including product education sessions for theatre staff.<\/p>\n<h2>Summary of DURASHEET Specifications<\/h2>\n<p>DURASHEET is a single-use, collagen-based implant made from medical-grade Type I bovine collagen purified beyond 99.9%. It functions as a biological substitute for the dura mater, providing a natural scaffold that supports sealing, tissue integration and healing across cranial and spinal neurosurgical applications. The membrane is terminally gamma sterilised, supplied ready to use, and resorbable, so it is replaced over time by the patient&#8217;s own connective tissue rather than remaining as a permanent implant. It can be trimmed with surgical scissors, sutured into the dural edge, or applied as an onlay depending on defect geometry and access. Manufacturing operates under an ISO 13485 certified quality system with CE certification for the product line, and biocompatibility has been evaluated across the ISO 10993 series including implantation response. Size and packaging options for your market can be confirmed by our commercial team.<\/p>\n<h2>Request Samples or the E-Catalogue<\/h2>\n<p>Detailed product information is published at <a href=\"https:\/\/desu.tr\/tr\/urun\/durasheet-collagen-dura-membrane\/\">desu.tr\/<\/a>, and the full e-catalogue is available on the same site. For evaluation samples, CE documentation, quotations or distribution enquiries, write to <a href=\"mailto:sales@desu.tr\">sales@desu.tr<\/a>.<\/p>\n<p><em>Information for healthcare professionals. Refer to the instructions for use.<\/em><\/p>\n<hr \/>\n<h2>About Desu Medical<\/h2>\n<p>Desu Medical is a medical research and development company founded in 2007 and headquartered in Ankara, Turkiye. The company designs and manufactures neurosurgical devices in-house, including hydrocephalus shunt systems, external ventricular drainage sets, catheters, intracranial pressure monitoring, bone grafts and the collagen dural graft range comprising <a href=\"https:\/\/desu.tr\/tr\/urun\/decoll-collagen-dura-membrane\/\">DECOLL<\/a> and <a href=\"https:\/\/desu.tr\/tr\/urun\/durasheet-collagen-dura-membrane\/\">DURASHEET<\/a>. Every dural graft is produced from more than 99.9% pure Type I bovine collagen sourced from controlled and traceable tissue, gamma sterilised, and supplied ready to use. Manufacturing operates under an ISO 13485 certified quality management system, the dural graft range carries CE certification, and biocompatibility has been evaluated across the ISO 10993 series. Desu supplies healthcare professionals internationally through direct institutional relationships and distribution partners. For product specifications, CE documentation, evaluation samples or quotations, visit <a href=\"https:\/\/desu.tr\/tr\/urun\/dura-grafts\/\">desu.tr\/<\/a> or contact the team at <a href=\"mailto:sales@desu.tr\">sales@desu.tr<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"<p>DURASHEET is a single-use collagen implant made from >99.9% pure Type I bovine collagen, engineered as a biological dura substitute for cranial and spinal repair.<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[75],"tags":[83],"class_list":["post-90106","post","type-post","status-publish","format-standard","hentry","category-dural-grafts","tag-durasheet"],"_links":{"self":[{"href":"https:\/\/desu.tr\/tr\/wp-json\/wp\/v2\/posts\/90106","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/desu.tr\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/desu.tr\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/desu.tr\/tr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/desu.tr\/tr\/wp-json\/wp\/v2\/comments?post=90106"}],"version-history":[{"count":0,"href":"https:\/\/desu.tr\/tr\/wp-json\/wp\/v2\/posts\/90106\/revisions"}],"wp:attachment":[{"href":"https:\/\/desu.tr\/tr\/wp-json\/wp\/v2\/media?parent=90106"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/desu.tr\/tr\/wp-json\/wp\/v2\/categories?post=90106"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/desu.tr\/tr\/wp-json\/wp\/v2\/tags?post=90106"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}