XENOBONE Bovine-Derived Collagen Graft
Bovine-Derived Collagen Bone Graft Matrix
For Reliable Osteoconduction and Regenerative Bone Healing
In reconstructive and regenerative surgeries involving bone tissue, success depends on the use of graft materials that not only fill voids but also support and guide new bone formation. XenoBone is Desu’s advanced answer to this challenge: a bovine-derived, collagen-based bone graft matrix designed to stimulate osteogenesis, accelerate healing, and integrate naturally into the human body.
Made with more than 95% ultra-pure Type I bovine collagen and supplemented with β-tricalcium phosphate (β-TCP), XenoBone offers a bioabsorbable, osteoconductive platform ideal for orthopedic, dental, spinal, and trauma-related bone grafting procedures. Its unique formulation is biologically inspired and clinically validated to encourage new bone growth while gradually resorbing and being replaced by the patient’s own bone tissue.
Engineered for Biologic Harmony
XenoBone is developed using high-purity Type I collagen, the primary collagen type found in natural bone and soft connective tissue. This biomimetic design allows for excellent biocompatibility and integration into the native bone remodeling process. The addition of β-TCP, a well-established bone-regenerative ceramic, provides essential calcium and phosphate ions to facilitate mineralization and scaffold reinforcement.
The matrix is highly porous, allowing for rapid vascular ingrowth, cellular migration, and nutrient diffusion. These features support the early stages of healing and transition into late-phase bone maturation. XenoBone does not simply serve as a space filler; it becomes an active participant in the regeneration process.
CE Marked and ISO Certified
XenoBone is manufactured by Desu under stringent quality systems and holds both CE certification and ISO quality management system compliance. These credentials ensure that XenoBone meets international standards for medical device safety, performance, and traceability.
The product is sterile, single-use, and fully traceable from manufacturing batch to patient application. All packaging and labeling meet regulatory expectations for surgical implantation devices, providing hospitals and clinicians with full assurance in both safety and efficacy.
Key Clinical Benefits
XenoBone was developed with a deep understanding of the clinical requirements of bone healing. Its unique structure and composition provide a series of significant benefits for surgeons and patients alike:
Osteoconductive and Osteoinductive Support
The Type I collagen matrix promotes osteoblast adhesion and proliferation, while β-TCP facilitates mineral deposition and new bone formation.
Bioabsorbable Scaffold
XenoBone is gradually resorbed and replaced by natural bone through the body’s own remodeling pathways, eliminating the need for secondary surgeries.
High Collagen Purity (>95%)
Ensures biocompatibility, mechanical resilience, and biological activity without triggering immune responses.
Growth Matrix for Osteoblasts
Provides a favorable microenvironment for cellular activity, enhancing the body’s ability to rebuild lost or damaged bone.
Safe and Easy to Use
Sterilized, pre-packaged, and available in various forms and sizes for different anatomical sites and surgical techniques.
Clinical Applications
XenoBone is a versatile and adaptive bone graft material suitable for use across a broad spectrum of orthopedic, maxillofacial, and dental procedures. Its structural properties make it appropriate for both load-bearing and non-load-bearing applications.
Common indications include:
Alveolar Ridge Augmentation
Filling of post-extraction sockets or alveolar defects before dental implant placement.
Sinus Lift Procedures
Supporting bone height restoration in the posterior maxilla to accommodate implant fixtures.
Periodontal Bone Defect Repair
Treatment of intrabony and furcation defects resulting from periodontal disease.
Cyst Enucleation and Apicoectomy
Filling of residual bone defects post-tumor or lesion removal.
Trauma Reconstruction
Filling of bone gaps resulting from fractures, crush injuries, or non-unions.
Orthopedic Bone Gaps
Used in combination with internal fixation devices in orthopedic surgeries requiring bone regeneration.
Spinal Fusion Procedures
Acting as a supplemental graft in posterolateral or interbody spinal fusion surgeries.
XenoBone is also suitable as an adjunct to autografts or allografts, reducing the amount of autologous bone harvesting needed and minimizing donor site morbidity.
Physical Forms and Sizes
To address the needs of varying defect shapes and clinical preferences, XenoBone is offered in different particle sizes and volume configurations, including both granules and spongiform (block) formats.
Reference Code | Product Description |
XBN-0715W-5CC | Collagen-Based Animal Derived Bone Graft 0.7–1.5 mm (5 cc) |
XBN-23W-5CC | Collagen-Based Animal Derived Bone Graft 2–3 mm (5 cc) |
XBN-45W-5CC | Collagen-Based Animal Derived Bone Graft 4–5 mm (5 cc) |
Each product is gamma sterilized and delivered in double-blister packaging to ensure aseptic delivery to the surgical field. The material is ready to use and requires no hydration or chemical treatment prior to implantation.
Handling Characteristics
XenoBone is designed for convenience and clinical confidence. It demonstrates:
Excellent wettability and cohesion
When exposed to blood or saline, the particles become cohesive and moldable.
Adaptability to defect shape
Can be packed into irregular defect geometries with ease.
Stability during placement
Retains shape and volume during surgical handling and suturing.
Compatibility with membranes
Works well with resorbable or non-resorbable barrier membranes in guided bone regeneration (GBR) procedures.
These characteristics make XenoBone a surgeon-friendly option that supports reproducible, predictable results.
Performance Backed by Science
Desu has conducted extensive biocompatibility and performance testing on XenoBone, confirming:
Cytotoxicity: Non-toxic to human cells
Sensitization: No allergic or immune responses
Irritation: Safe for local tissues
Systemic Toxicity: Free from harmful systemic effects
Implantation: Integrates well without adverse tissue response
Clinical studies and in vivo models support its osteoconductive properties and demonstrate a strong capacity for volumetric stability and bone regeneration over time.
Why Choose XenoBone?
In an increasingly demanding surgical environment, XenoBone delivers what both clinicians and patients need:
Reliable performance in bone regeneration
Excellent biocompatibility and handling
Reduced surgical time and donor site morbidity
CE-marked, ISO-certified quality assurance
Available in ready-to-use packaging and practical configurations
Whether you’re performing guided bone regeneration in a dental clinic or filling critical-sized defects in trauma surgery, XenoBone is a trusted companion that promotes biological healing and surgical efficiency.
Contact Desu
Would you like to receive more information about XenoBone, request product samples, or obtain CE documentation for institutional use?
English